منابع مشابه
The genetic landscape of anaplastic astrocytoma
Anaplastic astrocytoma WHO grade III (A3) is a lethal brain tumor that often occurs in middle aged patients. Clinically, it is challenging to distinguish A3 from glioblastoma multiforme (GBM) WHO grade IV. To reveal the genetic landscape of this tumor type, we sequenced the exome of a cohort of A3s (n=16). For comparison and to illuminate the genomic landscape of other glioma subtypes, we also ...
متن کاملBenefit with adjuvant chemotherapy in anaplastic astrocytoma.
www.thelancet.com Published online August 8, 2017 http://dx.doi.org/10.1016/S0140-6736(17)31477-0 1 The role of chemotherapy for newly diagnosed anaplastic gliomas, particularly when combined with radiotherapy, has long been unresolved. Over the past few decades, despite no conclusive data, study findings have suggested that the addition of nitrosourea-based chemotherapy to radiotherapy could b...
متن کاملMixed granular cell astrocytoma and fibrosarcoma of the brain: a case report.
We describe a rare primary mixed granular cell astrocytoma and fibrosarcoma neoplasm, occurring in a 52-year-old female, with morphologic, immunohistochemical and molecular genetic features, whose tumor was entirely composed of granular cells and fibrosarcoma competent. This represents, to the best of our knowledge, the first report of the mixed granular cell astrocytoma and fibrosarcoma neopla...
متن کاملAnaplastic astrocytoma post radiotherapy of pineal germinoma.
Dra. Martha Tena-Suck – Departamento de Neuropatología / Instituto Nacional de Neurología y Neurocirugía “Manuel Velasco Suárez” Av. Insurgentes Sur, 3788 Col. La fama, Delegación Tlalpan C.P. 14269 México DF México. E-mail: [email protected] Intracranial germ cell tumors (GCTs), especially pineal tumors have attracted the special attention of neuropathologists and neurosurgeons because of ...
متن کاملThe Role of Chemotherapy in Anaplastic Astrocytoma Patients
OBJECTIVE This retrospective study was performed to evaluate the role of chemotherapy in the management of patients with anaplastic astrocytoma (AA). METHODS We compared the survival outcome among the 3 different treatment protocol groups in a single institution. A total of 86 patients (39 men and 47 women) with newly diagnosed AA after surgery were analyzed. Among them, 31 patients (36.0%) w...
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ژورنال
عنوان ژورنال: Neurologia medico-chirurgica
سال: 1977
ISSN: 0470-8105,1349-8029
DOI: 10.2176/nmc.17pt2.391